The power windows on your Ford F-250 should give you years of trouble-free performance. However, over time, the power window module may wear out. The motor that powers the window scissor arms may also fail. These are the more serious problems that you can experience with your F-250's power windows. Usually, the problem is much simpler. However, you need to troubleshoot the issue before doing any repairs.
Open the fuse panel under the steering column by pulling down on the cover.
Pull the fuse for the power windows; use the fuse diagram to locate the fuse if you are having trouble finding it. Use the fuse puller in the fuse panel to remove the fuse.
Check the metal strip inside the fuse. The strip should not be burned or broken in any way. If it is, replace this fuse with a working fuse of the same amperage.
Check the power-window lock on your Ford F250. The power-window lock is located by the power-window button on the door armrest. If this accidentally gets switched to "lock," you won't be able to raise or lower the window with the lock engaged.
Listen to the window motor. If the motor sounds strained, it probably is a good sign that the motor is failing and needs to be replaced.
